the.scientist
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A Journey With Metabolism, Parasites, and Cancer
on December 4, 2023 at 10:00 pm
Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.
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Downsizing DNA
on December 4, 2023 at 5:00 am
Some species remove up to 90 percent of their genomes during development, but why or how this happens is still a mystery.
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Infographic: Phage Display Allows Rapid Screening of Millions of Peptides
on December 4, 2023 at 5:00 am
A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.
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A Story of FIRE and Mice
on December 4, 2023 at 5:00 am
Studying how microglia control myelin growth and prevent its degeneration helps scientists better understand and address neurodegenerative diseases.
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The Cre-loxP System: A Powerful Tool in the Genetic Toolbox
on December 4, 2023 at 5:00 am
Standing at the cornerstone of genetic research, Cre-loxP recombination serves as molecular scissors for precisely manipulating the genome.
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Infographic: Early Placenta Development Sets the Stage
on December 4, 2023 at 5:00 am
During early pregnancy, the placenta remodels the uterine environment to support fetal growth
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Infographic: Mitochondria, the Cellular Processors
on December 4, 2023 at 5:00 am
Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of […]
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When Scientists Collaborate, Science Progresses
on December 4, 2023 at 5:00 am
p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 13.0px; font: 10.0px Gotham} span.s1 {letter-spacing: 0.1px}Behind every successful scientist, there is […]
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Coming Into the Fold: DNA Origami
on December 4, 2023 at 5:00 am
In 2006, Paul Rothemund transformed the field of DNA nanotechnology when he unveiled an innovative approach for making shapes and patterns from genetic […]
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Infographic: Gene Activity in the Cellular Afterlife
on December 4, 2023 at 5:00 am
Low oxygen resuscitates gene transcription after death.
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Infographic: The Cre-lox System Explained
on December 4, 2023 at 5:00 am
The Cre-lox recombination method orchestrates remarkable genetic manipulations that remain a gold standard for transgenic mice.
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Infographic: Recombinase Polymerase Amplification in Action
on December 4, 2023 at 5:00 am
A rapid isothermal amplification technique enables pathogen identification and antibiotic resistance detection in low-resource settings.
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Whenever, Wherever: Taking DNA Amplification Outside the Lab
on December 4, 2023 at 5:00 am
Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.
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Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
on December 4, 2023 at 5:00 am
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
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December 2023 Interactive Crossword Puzzle
on December 4, 2023 at 5:00 am
Try your hand at a sciency brainteaser.
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Cells and Organelles
on December 4, 2023 at 5:00 am
Put on your thinking cap, and take on this fun challenge.
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Infographic: Programmed DNA Elimination
on December 4, 2023 at 5:00 am
Removing parts of the genome is a key step in some species’ development.
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A Microbial Link to Parkinson’s Diseasep.p1 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 13.0px; font: 10.0px Gotham} span.s1 {letter-spacing: -0.2px}
on December 4, 2023 at 5:00 am
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
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Tracking Down Innate Immune Cells in Multiple Sclerosis
on December 4, 2023 at 5:00 am
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
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Phage Display: Finding the One in a Million
on December 4, 2023 at 5:00 am
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
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Infographic: Microglia Influence Myelin Health
on December 4, 2023 at 5:00 am
In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related […]
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The Ephemeral Life of the Placenta
on December 4, 2023 at 5:00 am
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
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Rebranding Mitochondria
on December 4, 2023 at 5:00 am
As scientists realize the multifaceted role of mitochondria, some feel that the “powerhouse of the cell” analogy is out of date.
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Making Standards Exceptional
on December 4, 2023 at 5:00 am
p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 13.0px; font: 10.0px Gotham} span.s1 {letter-spacing: -0.2px}Samantha Maragh has taken on the difficult […]
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Engineered RNA Export From Living Cells
on December 1, 2023 at 5:00 am
A nondestructive approach for packaging, exporting, and delivering RNA provides a glimpse into the dynamic lives of cells.