the.scientist

Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.

Some species remove up to 90 percent of their genomes during development, but why or how this happens is still a mystery.

A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.

Studying how microglia control myelin growth and prevent its degeneration helps scientists better understand and address neurodegenerative diseases.

Standing at the cornerstone of genetic research, Cre-loxP recombination serves as molecular scissors for precisely manipulating the genome.

During early pregnancy, the placenta remodels the uterine environment to support fetal growth

Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of […]

p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 13.0px; font: 10.0px Gotham} span.s1 {letter-spacing: 0.1px}Behind every successful scientist, there is […]

In 2006, Paul Rothemund transformed the field of DNA nanotechnology when he unveiled an innovative approach for making shapes and patterns from genetic […]

Low oxygen resuscitates gene transcription after death.

The Cre-lox recombination method orchestrates remarkable genetic manipulations that remain a gold standard for transgenic mice.

A rapid isothermal amplification technique enables pathogen identification and antibiotic resistance detection in low-resource settings.

Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

Try your hand at a sciency brainteaser.

Put on your thinking cap, and take on this fun challenge.

Removing parts of the genome is a key step in some species’ development.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.

A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.

In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related […]

Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.

As scientists realize the multifaceted role of mitochondria, some feel that the “powerhouse of the cell” analogy is out of date.

p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 13.0px; font: 10.0px Gotham} span.s1 {letter-spacing: -0.2px}Samantha Maragh has taken on the difficult […]

A nondestructive approach for packaging, exporting, and delivering RNA provides a glimpse into the dynamic lives of cells.